A Beginner's Guide to Blood Cells by Barbara J. Bain

By Barbara J. Bain

This renowned notebook has been updated and expanded all through, delivering a concise view of diagnostic haematology, in a handy and useful format.

A Beginner's consultant to Blood Cells is a perfect for;

  • Trainee laboratory technicians and scientists
  • Students learning the body structure or pathology of the blood
  • Those getting ready for haematology examinations

Why purchase This Book?

  • Unique pocket advisor, written through Barbara Bain – a world-renowned specialist within the box of blood morphology
  • Outlines the fundamentals of diagnostic haematology
  • Includes a useful self-assessment section
  • NEW EDITION – now contains additional information on medical features and extra tests
  • Show description

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Additional info for A Beginner's Guide to Blood Cells

Example text

One performed with the aid of a microscope. Learning to look at blood films When learning to recognize cells for the first time it is useful to compare cells seen down the microscope with photographs. Examining films on a double-headed microscope with an experienced laboratory worker is also very valuable. To learn to recognize high and low WBC and platelet counts, start by comparing the film appearance with the count on an automated instrument. After you have had some experience try to estimate what the count will be before you look at the test results.

This is known as right shift. Neutrophils with six or more lobes are said to be hypersegmented. Neutrophil hypersegmentation is an important clue to the presence of deficiency of vitamin B12 or folic acid. Macropolycytes (Fig. 8) should not be confused with hypersegmented neutrophils: they are twice the size of normal neutrophils and the nucleus is twice as big. This is because one cell division has been missed during neutrophil production. Macropolycytes are likely to have 92 Fig. 6 A neutrophil with two very round lobes in a patient with the congenital Pelger–Huët anomaly.

Basophilic stippling refers to the presence of small basophilic inclusions distributed throughout the red cell (Fig. 27). They do not contain iron but represent abnormally staining ribosomes. Howell–Jolly bodies (Fig. 28) are larger, round, densely staining inclusions, usually towards one edge of the cell. They represent a nuclear fragment that was not extruded when the red cell left the bone marrow. Usually any Howell– Jolly bodies left in red cells as they leave the bone marrow are removed by the spleen.

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