Advances in statistical methods for the health sciences : by Jean-Louis Auget; et al

By Jean-Louis Auget; et al

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Extra resources for Advances in statistical methods for the health sciences : applications to cancer and AIDS studies, genome sequence analysis, and survival analysis

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Altman et al. The general idea of an IPD systematic review is that the raw data for each individual are obtained directly from the researchers/data owners irrespective of whether a particular study has been published. , if extended follow up information is available). The data are (re-)analysed centrally by the review group using consistent statistical methods, including meta-analysis if appropriate. IPD meta-analyses have most famously been carried out by the Early Breast Cancer Trialists Collaborative Group (1998) when evaluating the impact of therapies for early breast cancer.

P53 immunohistochemistry as a prognostic marker in bladder cancer. Playground for urology scientists? European Urology, 38, 691–699. 25. , Brancati, F. , Powe, N. , and Golden, S. H. (2004). Meta-analysis: Glycosylated hemoglobin and cardiovascular disease in diabetes mellitus, Annals of Internal Medicine, 141, 421–431. 26. Simon, R. (2001). , M. K. Gospodarowicz, D. E. Henson, R. V. P. Hutter, B. O’Sullivan, L. H. Sobin, and C. Wittekind), pp. 49–56, Wiley-Liss, New York. 27. , and Altman, D. G.

While they often explore several factors simultaneously, many studies examine the prognostic importance of a single specified variable, such as a tumour marker. Such studies are the focus of this paper. The number of published prognostic studies continues to grow, but unfortunately additional studies have often led to more confusion than clarification [Simon and Altman (1994)]. As multiple similar studies accumulate, it becomes increasingly important to identify and evaluate all of the relevant work in or3 4 D.

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