Chemokine Receptors and AIDS (Infectious Disease and by Obrien

By Obrien

This authoritative reference offers the newest learn at the position of chemokines, chemokine receptors, and genetic variability within the susceptibility, prevention, and therapy of HIV-1-exploring new healing suggestions for more suitable remedy of HIV-1 contaminated sufferers via blocking off chemokine receptor expression. With contributions from pro specialists within the box, Chemokine Receptors and AIDS information ·the position of chemokine receptors in HIV-1 an infection and pathogenesis ·the id and function of the CCR5-D32 allele in HIV an infection ·potential novel the way to deal with HIV-1 an infection through blocking off or down-regulating the CCR5 and CXCR4 HIV-1 coreceptors ·strategies utilizing monoclonal antibodies, small molecules, and ribosymes ·and extra! providing greater than 1200 present references, Chemokine Receptors and AIDS is a necessary reference for infectious affliction experts, epidemiologists, virologists, immunologists, pharmacologists, medicinal chemists and biochemists, microbiologists, and clinical scholars in those disciplines.

Show description

Read Online or Download Chemokine Receptors and AIDS (Infectious Disease and Therapy) PDF

Best hematology books

Allogeneic Stem Cell Transplantation (Current Clinical Oncology)

The world over well-known physicians and researchers evaluation either the fundamentals of allogeneic stem telephone transplantation and up to date advances within the box, fairly as they relate to antitumor results and graft-versus-host illness in addition they supply exact decision-tree analyses to lead clinicians in making a choice on and handling their allogeneic transplant sufferers.

Jak-Stat Signaling : From Basics to Disease

JAK tyrosine kinases and STAT transcription elements represent a signaling pathway, that is activated via cytokines. by way of activating gene transcription it regulates crucial organic responses to environmental cues. The Jak-Stat pathway is inquisitive about the legislation of phone improvement, differentiation, proliferation and apoptosis.

Molecular Testing in Cancer

Molecular checking out in melanoma presents a state-of-the-art evaluate of clinically proper molecular pathology in melanoma. The booklet offers a quick, effortless to learn overview of generally hired diagnostic molecular ideas together with lately built "next iteration" analytic instruments, and gives a system-based run-through of the software of molecular checking out in person melanoma forms, in addition to reviewing present markers in melanoma prognosis, analysis, and administration.

Linked by Blood: Hemophilia and AIDS

Associated by means of Blood: Hemophilia and AIDS recounts the standards chargeable for the common an infection of individuals with hemophilia by means of Human Immunodeficiency Virus (HIV)-contaminated blood and gives a prescription for addressing the demanding situations of destiny viral epidemics. The e-book describes the effect of AIDS on individuals with hemophilia, their households, and caregivers.

Additional resources for Chemokine Receptors and AIDS (Infectious Disease and Therapy)

Example text

Oppenheim, OJ. O. Taub. 1996. Chemokines regulate t-cell adherence to recombinant adhesion molecules and extracellular-matrix proteins. Journal ofImmunology 156:932. 24. , 1. Hedrick, A. A. C. Butcher. 1998. Chemokines and the arrest of lymphocytes rolling under flow conditions. Science 279:381. 25. A. A. Steeber, TF. Tedder, O. O. Patel. 1998. Fractalkine and CX3CR I mediate a novel mechanism of leukocyte capture, firm adhesion, and activation under physiologic flow. J Exp Med 188(8): 1413-9. Copyrighted Material Chemokines and Chemokine Receptors 23 26.

L. Rymo, and GX Hansson. 1991. Polyclonal origin ofT lymphocytes in human atherosclerotic plaques. Lab. Invest. 65:654. 97. , AK Ulfgren, P. Nyberg, U. Hedin, 1 Swedenborg, U. K Hansson. 1999. Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th I) and macrophage-stimulating cytokines [In Process Citation]. Atherosclerosis 145:33. 98. 1. Nelson, P. K. Sibley, and AM. Krensky. 1996. RANTES chemokine expression in transplant-associated accelerated atherosclerosis.

1997. Targeted disruption of the chemokine eotaxin partially reduces antigen- induced tissue eosinophilia. Med. 185:785. 89. , S. Cooper, G. L. Hague, E. W. Moore. 1996. Involvement of Interleukin (lL) 8 receptor in negative regulation of myeloid progenitor cells in vivo: evidence from mice lacking the murine IL-8 receptor homologue. Med. 184:1825. 90. , 1. M. Ryan, S. Pitts-Meek, B. I. Wood, and M. W. Moore. 1994. Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog [published erratum appears in Science 1995 Oct 20;270(5235):365].

Download PDF sample

Rated 4.19 of 5 – based on 16 votes